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借助聚吡咯(PPy)的调控,采用脉冲电沉积法在生物医用金属钛表面制备出均匀的纳米HA/PPy/Ag抗菌复合涂层.考察了电解液中Py浓度、Ag~+浓度、钙磷盐浓度等对复合涂层的形貌及成分的影响.探讨了PPy聚合过程形成球形HA-NPs和Ag-NPs的形成机理,并对复合涂层的生物活性、生理稳定性及抗菌性能进行研究.研究结果表明,电解液中Py浓度的高低影响涂层的形貌,Py浓度为0.03 mol/L时有利于复合涂层的沉积.电解液中Ag~+浓度影响涂层的形貌、结晶,电解液中Ag~+浓度为0.3 mmol/L左右比较适合.电解液中Ca~(2+)浓度影响涂层的形貌及结晶,其浓度过高颗粒尺寸增大,Ca~(2+)浓度为5.0 mmol/L左右较适合.复合涂层能够诱导磷灰石的生成,使其沿着(002)晶面出现择优生长,具有较好的生物活性.PPy的加入大大降低了复合涂层中Ca~(2+)和Ag~+的释放速度,提高了复合涂层的生理稳定性.抗菌检测表明复合涂层具有良好的抗菌性.
With the help of polypyrrole (PPy), the uniform nano HA / PPy / Ag antimicrobial composite coating was prepared on the surface of biomedical titanium by pulsed electrodeposition.The effects of Py concentration, Ag ~ + concentration, Salt concentration on the morphology and composition of composite coatings.The formation mechanism of spherical HA-NPs and Ag-NPs during the polymerization of PPy was discussed, and the biological activity, physiological stability and antibacterial properties of composite coatings were studied The results show that the Py concentration in the electrolyte affects the morphology of the coating, which is beneficial to the deposition of the composite coating when the concentration of Py is 0.03 mol / L. The concentration of Ag + in the electrolyte affects the morphology of the coating and crystallization , And the concentration of Ag ~ + in the electrolyte is about 0.3 mmol / L. The concentration of Ca ~ (2+) in the electrolyte affects the morphology and crystallization of the coating and the concentration of Ca ~ (2+) ) Concentration of 5.0 mmol / L is more suitable for the composite coating can induce the formation of apatite, so that along the (002) crystal face preferential growth, has good biological activity. PPy greatly reduced the composite coating The release rate of Ca 2+ and Ag + in the layer increased the physiological stability of the composite coating. Coatings with good antibacterial property.