The interaction between stress and galvanic during the corrosion process of 5050 aluminum alloys was studied and the evolution of mechanics properties was indicated. Electrochemical impedance technique and scanning electron microscopy were used to analyze the surface electrochemical states and the corrosion morphology. At the same time, corrosion kinetics and thermodynamic theory were used to analyze the influencing mechanism of the stress factor and the galvanic factor. The results show that both of galvanic factor and tensile stress factor can increase the corrosion potential of aluminum alloys and result in the corrosion resistance decrease. With decreasing corrosion resistance, the mechanical properties of aluminum alloys decrease. These phenomena are attributed to two reasons: One is that aluminum alloys may under the condition of anodic polarization after coupled with 40CrNiMoA steel, so the corrosion can be promoted; The other is that with increasing stress, the electrochemical potential of 5050 aluminum alloys decreases and the potential difference between two materials increases, so the corrosion becomes serious. Compared to the stress factor, the galvanic factor is significant.