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目的观察晚期妊娠孕妇凝血指标水平变化,为预防产后出血及血栓形成提供依据。方法采用散射光凝固法检测晚期妊娠孕妇176名(晚妊组)、早期妊娠孕妇165名(早妊组)、非妊娠育龄妇女140名(非妊组)凝血酶原时间、活化部分凝血酶原时间、凝血酶时间及纤维蛋白原;并检测3组血小板计数。结果晚妊组凝血酶原时间、活化部分凝血酶原时间、凝血酶时间及纤维蛋白原水平与非妊组、早妊组比较差异有统计学意义(P<0.05);早妊组纤维蛋白原水平与非孕组比较差异有统计学意义(P<0.05);3组血小板计数比较差异无统计学意义(P>0.05)。结论晚期妊娠孕妇血液处于高凝状态。
Objective To observe the change of coagulation index in pregnant women of late pregnancy and provide the basis for prevention of postpartum hemorrhage and thrombosis. Methods One hundred and seventy-six pregnant women (late pregnancy group), 165 pregnant women (early pregnancy group), 140 non-pregnant women (non-pregnancy group) prothrombin time, partial prothrombin Time, thrombin time and fibrinogen; and three groups of platelet count. Results Prothrombin time, partial prothrombin time, thrombin time and fibrinogen level in late pregnancy group were significantly different from those in non-pregnancy group and early pregnancy group (P <0.05); early pregnancy group fibrinogen (P <0.05). There was no significant difference in platelet count between the three groups (P> 0.05). Conclusion The blood of pregnant women in late pregnancy is hypercoagulable.