p53基因是一种十分重要的抑癌基因,在机体组织细胞的生长、发育、分化等过程中起重要作用。p53基因丢失、缺失或突变可以导致人类恶性肿瘤的发生,而且与肿瘤的分化程度相关。目前,以p53基因治疗肿瘤的研究发展非常迅速,利用p53基因治疗肿瘤已成为继手术、放疗、化疗后的又一种有希望的肿瘤生物治疗方法。最近,有学者引入介入技 The p53 gene is a very important tumor suppressor gene, which plays an important role in the growth, development and differentiation of the tissue cells of the body. p53 gene loss, deletion or mutation can lead to the occurrence of human malignant tumors, but also with the degree of tumor differentiation. At present, the research on the treatment of tumors by p53 gene has been developed rapidly. The use of p53 gene in the treatment of tumors has become another promising tumor biotherapy method after surgery, radiotherapy and chemotherapy. Recently, some scholars have introduced interventional techniques