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维生素K_3(VK_3)主要用作临床药物及饲料添加剂。另外,VK_3还可在植物生长调解剂、促进剂、除草剂等领域应用,前景也十分广阔。因此,其生产技术研究具有十分重要的现实意义。目前国内VK3实际产量不足100吨,远远不能满足需求,每年不得不从国外进口,以满足市场需求。由于我国具有丰富的β-甲基萘(β-MN),故国内VK_3生产工艺均采用以β-MN为原料,经氧化制得β-甲基-1,4-萘醌(β-MNQ),再经磺化、精制等程序获得成品VK_3。目前我国的β-MN氧化工艺大体有3种,第一是重铬酸钠加硫酸作为氧化剂,用丙酮萃取生成β-MNQ,氧化生成的废铬液经中和、沉锭、煅烧等后处理制得铬绿。该工艺产
Vitamin K3 (VK3) is mainly used as a clinical drug and feed additive. In addition, VK_3 can also be applied in the field of plant growth mediators, accelerants, herbicides, etc. The prospects are also very broad. Therefore, the research of its production technology has very important practical significance. At present, the actual output of domestic VK3 is less than 100 tons, far from meeting the demand, and it has to be imported from abroad each year to meet market demand. Because China has abundant β-methylnaphthalene (β-MN), the domestic VK_3 production process adopts β-MN as raw material and oxidized to obtain β-methyl-1,4-naphthoquinone (β-MNQ). , Sulfonation, refining and other procedures to obtain the finished product VK_3. At present, there are three kinds of β-MN oxidation processes in China. The first is that sodium dichromate plus sulfuric acid is used as an oxidant and extracted with acetone to form β-MNQ. The waste chromium solution generated by oxidation is neutralized, immersed, and calcined. Chrome green. The production process