羟乙基淀粉(HES)是临床常用的血浆代用品之一,因过敏发生率低,无生物制品感染危险而广泛使用,属于新一代中相对分子质量的、低取代级的人工合成胶体液,根据其分子质量和取代级别的不同划分成许多类型。现已表明HES具有降低血液黏度、改善血流动力学、扩充血容量、提高组织氧供、进而改变微循环、抑制炎症等作用。 Hydroxyethyl starch (HES) is one of the commonly used clinical plasma substitutes. It is widely used as a new generation of relatively low molecular weight, low substituted synthetic colloidal solution due to its low incidence of allergy and no risk of biological infection. According to their molecular weight and level of substitution into many different types. HES has been shown to reduce blood viscosity, improve hemodynamics, expand blood volume, improve tissue oxygen supply, thus changing the microcirculation, inhibit inflammation and so on.