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糖尿病患者常伴有胃肠道运动异常,常用胃肠动力药物治疗。红霉素是抗生素中唯一胃动素受体激动剂,对胃肠具有胃动素样作用,能促进胃肠蠕动。笔者试用红霉素治疗糖尿病胃活动低下18例,取得较满意疗效,现报道如下: 1 临床资料 1.1 一般资料 男13例,女5例,年龄48～74岁。糖尿病病程4～13年。血糖8～11.1mmol/L10例,11.1mmol/L以上8例。所有病例均有上腹胞胀不适、恶心、厌食、少数伴有呕吐,上述症状以餐后加重。全部病例均经钡餐造影显示有不同程度的胃扩张、胃蠕动减弱、蠕动波<2/3;胃排空延迟、半小时胃排空<3/5;并排除胃十二指肠溃疡、幽门梗阻、肿瘤等。18例患者均
Diabetic patients often accompanied by gastrointestinal motility disorders, commonly used gastrointestinal motility drug treatment. Erythromycin is the only motilin receptor agonist in antibiotics, with motilin-like effect on the gastrointestinal tract, can promote gastrointestinal motility. The author trial of erythromycin in diabetic patients with low gastric activity in 18 cases, to obtain more satisfactory efficacy, are reported below: 1 Clinical data 1.1 General Information 13 males and 5 females, aged 48 to 74 years. Diabetes duration of 4 to 13 years. Blood glucose 8 ~ 11.1mmol / L10 cases, 11.1mmol / L or more in 8 cases. All cases have abdominal distension discomfort, nausea, anorexia, a few with vomiting, the symptoms of postprandial aggravate. All cases were barium meal angiography showed varying degrees of gastric distension, weakened gastric motility, peristaltic wave <2/3; delayed gastric emptying, half an hour gastric emptying <3/5; and exclude gastric ulcer, pylorus Obstruction, cancer and so on. 18 patients were