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目的观察珂立苏联合鼻塞式同步间歇指令通气(nSIMV)治疗早产儿呼吸窘迫综合征的临床疗效。方法给予19例患呼吸窘迫综合征的早产儿行气管插管,经气管内注入珂立苏后拔管,给予nSIMV辅助呼吸,观察应用珂立苏前后血气、X线胸片、nSIMV参数的变化。结果 19例患儿用药后体征、血气、呼吸参数明显改善,与治疗前比较差异有统计学意义(P<0.05),均顺利撤除nSIMV,未出现并发症。结论珂立苏联合nSIMV治疗早产儿呼吸窘迫综合征安全有效。
Objective To observe the clinical efficacy of Coriolis combined nasal block syndromic intermittent mandatory ventilation (nSIMV) in the treatment of respiratory distress syndrome in premature infants. Methods Nineteen premature infants with respiratory distress syndrome were treated by endotracheal intubation, extubated by cilestrex after intratracheal intratracheal intratracheal instillation, and nSIMV assisted breathing. The changes of blood gas, X-ray and nSIMV parameters before and after application of clofazim . Results The signs, blood gas and respiration parameters of 19 children were significantly improved after treatment, with statistical significance (P <0.05). The nSIMV was successfully removed and no complication occurred. Conclusion Coriolis combined nSIMV treatment of respiratory distress syndrome in preterm children safe and effective.