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目的:探讨次声作用对大鼠视觉电生理的影响. 方法:42 只大鼠按暴露时间随机分为7 组,每组 6 只,暴露于 8 Hz,130 d B的次声压力仓中,2 h/d,分别暴露1,4,7,11,14,18及21 d,暴露前后分别行闪光视觉诱发电位( F V E P)、视网膜电图( E R G)、振荡电位( O Ps)的检测. 结果:动物在次声暴露1d 后,即有明显 F V E P P波、 E R Ga 波、 E R Gb 波振幅下降,而且随着暴露时间延长,有明显的适应现象: F V E P P波在暴露18 d 后,振幅下降有所恢复; E R Ga 波、 E R Gb 波恢复后也直到暴露14 d,才再次出现振幅的明显下降. Σ O Ps 的振幅随着次声暴露时间的延长,振幅下降随之增多. 结论:次声确可造成一定程度的视觉功能的损害. 这种作用不仅通过中枢反应间接引起视觉机能的异常,还有可能通过能量转换直接造成视网膜血液供应的改变,而影响神经传导.
Objective: To investigate the effect of infrasound on visual electrophysiology in rats. Methods: Forty-two rats were randomly divided into 7 groups according to exposure time, with 6 rats in each group. They were exposed to infrasound pressure of 8 Hz and 130 d B for 2 h / d, respectively. FV E P, E R G and O Ps were detected before and after exposure on days 14, 18 and 21, respectively. Results: The animals showed significant F V E P-P wave after 1 day of infrasound exposure. The amplitudes of E R Ga wave and E R Gb wave decreased, and with the prolongation of exposure time, there was obvious adaptation phenomenon: F V E P-P wave amplitude after 18 d exposure has been restored; E R G aa wave, E R G b wave recovery is not exposed until after 14 d, again significant amplitude decline. The amplitude of Σ O Ps decreases with the increase of infrasound exposure time. Conclusion: infrasound can indeed cause some damage to visual function. This effect not only indirectly through the central reaction caused by abnormal visual function, but also may be directly caused by energy conversion retinal blood supply changes, and affect nerve conduction.