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目的探讨比索洛尔与胺碘酮联合使用治疗急性心肌梗死(AMI)的预后情况与安全性影响。方法以2010年1月至2012年11月新乡公立医院收治的110例AMI患者为研究对象,分为观察组55例与对照组55例。对照组患者给予美托洛尔,观察组则给予比索洛尔与胺碘酮治疗,对比两组患者心律失常的发生率、治疗前后的QTcd情况及患者预后。结果与对照组相比,观察组患者的病死率、心律失常发生情况均明显降低,QTcd也显著降低,差异有统计学意义(P<0.05)。结论比索洛尔与胺碘酮联合使用可以显著改善AMI患者的预后,有效降低患者心律失常的发生率,安全可靠。
Objective To investigate the prognosis and safety of bisoprolol combined with amiodarone in the treatment of acute myocardial infarction (AMI). Methods From January 2010 to November 2012 in Xinxiang Public Hospital, 110 cases of AMI patients were divided into observation group 55 cases and control group 55 cases. Patients in the control group received metoprolol, while those in the observation group received bisoprolol and amiodarone. The incidence of arrhythmia, QTcd before and after treatment, and prognosis were compared between the two groups. Results Compared with the control group, mortality and arrhythmia in the observation group were significantly decreased, QTcd was also significantly decreased, the difference was statistically significant (P <0.05). Conclusion The combination of bisoprolol and amiodarone can significantly improve the prognosis of patients with AMI, effectively reduce the incidence of arrhythmia in patients with safe and reliable.