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目的评价非创伤性充填治疗儿童乳牙和恒牙龋的效果。方法计算机检索Cochrane图书馆临床对照试验资料库(CENTRAL)、MEDLINE、EMbase、中国生物医学文献数据库、中国期刊全文数据库和维普科技期刊全文数据库,同时检索中国临床试验注册中心等,检索时间均从建库至2010年4月。搜集非创伤性充填(ART)和常规充填(CRT)比较治疗儿童龋病的随机对照试验(RCT)。由两位研究者独立进行资料提取和质量评价后,采用RevMan 5.0.2软件进行Meta分析。结果共纳入7个RCT。因各研究采用不同的充填材料,受试牙的种类、测量指标及随访年限不一样,故仅进行描述性分析。结果显示:多数研究显示ART组各类洞形的充填体保存率与传统去腐组相当,仅个别研究显示CRT组优于ART组;治疗过程中接受ART治疗的儿童较CRT组儿童感觉舒适;2个研究比较了两组的工作时间,但结果相反。结论由于纳入研究临床异质性较大,无法进行合并分析,故对ART与CRT比较治疗儿童龋病的疗效尚不能得出确切结论,尚需更多高质量的研究加以验证。
Objective To evaluate the effect of non-invasive filling on deciduous teeth and permanent teeth in children. Methods The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMbase, Chinese Biomedical Literature Database, Chinese Journal Full-text Database and VIP Scientific Journal Full-text Database were searched by computer. The Chinese clinical trial registration center was retrieved by computer. Library until April 2010. A randomized controlled trial (RCT) comparing non-traumatic (ART) and conventional (CRT) pediatric caries was collected. After two researchers independently conducted data extraction and quality evaluation, Meta-analysis was performed using RevMan 5.0.2 software. Results A total of 7 RCTs were included. Due to the different filling materials used in each study, the types of test teeth, measurement indexes and follow-up years are different, so only descriptive analysis. The results showed that most of the researches showed that the retention rate of all kinds of cavities in ART group was comparable to that of traditional decortication group. Only a few studies showed that CRT group was better than ART group. ART treatment children felt more comfortable than CRT group. Two studies compared the working hours of both groups, but the opposite result. Conclusion Because of the large clinical heterogeneity and the inability to carry out the combined analysis, the curative effect of ART and CRT on the treatment of children’s dental caries can not be concluded yet. More high-quality studies are needed to verify the curative effect.