Elevated serum Hs-CRP level may be an independent predictor of metabolic syndrome (MS) in healthy individuals.Many elderly patients have metabolic syndrome.Therefore,we observed the clinical features of serum Hs-CRP level in elderly patients with metabolic syndrome to further understand the relationship between the two.Methods A total of 210 patients were divided into two groups:metabolic syndrome(MS,n=1112) group and non-metabolic syndrome (Non-MS,n=98) group.The serum Hs-CRP level was tested by immunoturbidimetry and the clinical features of Hs-CRP were analyzed.The associations of Hs-CRP with BMI,WHR,FBG,TG,TC,LDL-C,HDL-C,SBP,DBP and Homa-IR were determined.Results Serum HsCRP level was significantly higher in the MS group than in the non-MS group (P＜0.05).Besides,with the increase in the number of included factors,the level of Hs-CRP gradually increased significantly (P＜0.05).Moreover,serum Hs-CRP was positively correlated with age,BMI,WHR,SBP,DBP,FPG,FIN,TG,TC,Homa-IR (r=0.38,0.49,0.33,0.36,0.31,0.34,0.43,0.37,0.18,0.34,respectively,P＜0.05) and negatively correlated with HDL-C(r=-0.37,P＜0.001).Conclusion Serum Hs-CRP level is associated with many factors.It is a proactively marker for cardiovascular disease risk assessment of elderly MS patients.