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目的探究不同孕周开始治疗妊娠梅毒患者对妊娠结局的影响。方法选择2010年1月至2014年2月收治的妊娠梅毒患者126例,依据开始进行诊治的孕周不同分为孕周>16周组61例,孕周≤16周组65例,对两组患者施行同一治疗方案,比较两组患者的新生儿娩出情况及妊娠结局等指标。结果孕周>16周组患者新生儿阿氏评分与体重均明显低于孕周≤16周组,差异有统计学意义(P均<0.01),≤16周组正常足月活婴数显著优于>16周组,差异有统计学意义(P<0.01);≤16周组先天梅毒、早产儿与足月小样儿例数明显低于>16周组(P<0.05,P<0.01);两组均未出现死产儿。结论对妊娠梅毒开始诊治的孕周进行分期,能够较好的指导临床治疗,有效降低妊娠风险,使新生儿相对健康安全,临床应用价值较高。
Objective To investigate the effect of gestational weeks on the treatment of pregnant women with syphilis on pregnancy outcome. Methods 126 pregnant women with syphilis from January 2010 to February 2014 were enrolled in this study. According to the gestational age at the beginning of diagnosis and treatment, there were 61 cases of gestational age> 16 weeks, 65 cases of gestational weeks ≤ 16 weeks, Patients with the same treatment, compared the two groups of patients with neonatal delivery and pregnancy outcome and other indicators. Results The gestational age> 16 weeks group neonatal Asahi score and body weight were significantly lower than the gestational age ≤ 16 weeks group, the difference was statistically significant (P all <0.01), ≤ 16 weeks group normal full-term live baby significantly The number of cases of congenital syphilis, premature babies and full - term children less than 16 weeks group was significantly lower than that of> 16 weeks group (P <0.05, P <0.01) at> 16 weeks group. The difference was statistically significant (P <0.01). No childbirth occurred in either group. Conclusion The staging of gestational weeks for the diagnosis and treatment of syphilis in pregnancy can guide the clinical treatment effectively, reduce the risk of pregnancy, make the newborn relatively healthy and safe, and have higher clinical value.