洋金花的法医毒理学研究 Ⅱ、急性毒性的测定

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洋金花(曼陀罗)是常用的中草药,在临床上用于麻醉,治疗慢性气管炎和精神分裂症等症。洋金花又是有毒的植物,关于其中毒乃至误食致死的报道屡见于文献。“其花、叶、果实、种子均能使人中毒,中毒的时间一般以深秋(九、十月份)为多,以果实和种子中毒为主。”洋金花的有毒成份主要是生物碱。包括阿托品、莨菪碱和东莨菪碱。根据《全国中草药汇编》报道,“曼陀 Ocean Gold (Mandala) is a commonly used Chinese herbal medicine, used clinically for anesthesia, treatment of chronic bronchitis and schizophrenia embolism. Ocean flower is poisonous plants, reports on its poisoning and even death caused by eating frequently found in the literature. “Its flowers, leaves, fruits, seeds can make people poisoning, poisoning time generally late autumn (September and October) as much as the fruit and seed poisoning.” The poisonous constituents of the genus is mainly alkaloids. Includes atropine, hyoscyamine and scopolamine. According to the “National Collection of Chinese Medicine,” reported that "Mando
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