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目的:分析左氧氟沙星不同用法对女性生殖道支原体感染患者疗效的成本-效果。方法:采用随机对照单盲法,分析左氧氟沙星1日1次给药和1日2次给药方案对女性生殖道支原体感染患者的有效率、细菌清除率、ADR发生率和治疗成本-效果。结果:两种给药方案的治愈率分别为80.00%和57.69%(P<0.05);成本-效果比分别为6.28和8.16;ADR发生率分别为7.06%和8.97%(P>0.05)。结论:左氧氟沙星1日1次给药方案的成本-效果优于1日2次给药方案,治疗女性生殖道支原体感染患者应采用左氧氟沙星1日1次给药治疗。
Objective: To analyze the cost-effectiveness of the different usage of levofloxacin in the treatment of female genital Mycoplasma infection. Methods: The efficacy, bacterial clearance rate, incidence of ADR and cost-effectiveness of levofloxacin on patients with mycoplasma genital tract infection were analyzed by single-blind randomized controlled trial. Results: The cure rates of the two regimens were 80.00% and 57.69% respectively (P <0.05). The cost-effect ratios were 6.28 and 8.16 respectively. The incidences of ADR were 7.06% and 8.97% (P> 0.05). CONCLUSION: The cost-effectiveness of levofloxacin once a day administration scheme is better than that of twice a day. For patients with genital mycoplasma infection, levofloxacin should be given once a day for treatment.