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目的观察类风湿关节炎患者的疾病活动指数,分析治疗2年后患者缓解率及相关因素。方法调查100例类风湿关节炎患者,比较治疗前后关节压痛数、肿胀数、血沉、患者的总体评估(VAS),分析2年后的缓解率及相关因素。结果 2年后随访率为46%,失访率为54%,缓解率为42%,未缓解率为58%;治疗2年后关节的肿胀数、压痛数、血沉及VAS均明显下降;缓解者DAS28与病程、年龄、晨僵时间的相关性分析显示之间并无相关性。结论通过分析类风湿关节炎患者的疾病活动指数,了解疾病的活动程度,定期给予患者疾病评估,指导治疗;同时增强患者的教育意识,提高随访率。
Objective To observe the disease activity index of patients with rheumatoid arthritis and analyze the patients’ remission rate and related factors after 2 years of treatment. Methods 100 patients with rheumatoid arthritis were investigated. The tenderness, swelling, erythrocyte sedimentation rate, total assessment (VAS) of the patients before and after treatment were compared. The response rate and related factors after 2 years were analyzed. Results The follow-up rate was 46% after 2 years, the rate of follow-up was 54%, the rate of remission was 42% and the rate of non-remission was 58%. The number of swelling, tenderness, erythrocyte sedimentation rate and VAS were significantly decreased Correlation analysis of DAS28 with duration, age and morning stiffness showed no correlation. Conclusion By analyzing the disease activity index of patients with rheumatoid arthritis to understand the degree of disease activity, regular evaluation of patients with disease, to guide treatment; while enhancing patient awareness of education and increase follow-up.