一种过早衰老小鼠动物模型的戏剧性返老还童,是否暗示了一种潜在的治疗学方案?一项对小鼠动物模型的研究提示:过早衰老可以通过恢复一种保护染色体末端的酶——端粒酶——的活性得到逆转。通过遗传工程的操作,科学家们使缺乏端粒酶的小鼠出现了早发性衰老。然而,当端粒酶被替换掉后,它们又很快恢复到健康状况,这一发现发表 Does a dramatic rejuvenation of an animal model of premature aging suggest a potential therapeutic regimen? A study of mouse models suggests that premature aging can be achieved by restoring an enzyme that protects the end of the chromosome - Telomerase activity was reversed. Through genetic engineering operations, scientists have shown that telomerase-deficient mice develop premature senility. However, when telomerase was replaced, they quickly returned to their healthy state, a finding that was published