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本文报告系统性红斑狼疮(简称SLE)8例,均做了尸体解剖检查并发现心、肺和肾等多脏器损害。全部病例的心脏临床表现均较病理改变轻微,其中两例X线未发现心脏及肺循环异常。心脏增大的病理基础是SLE侵及心脏全层与心包;高血压是导致心脏增大的另一个主要因素。左心衰竭产生肺静脉高压;胸部病变及肺小动脉玻璃样变性可导致肺动脉高压。
This article reports 8 cases of systemic lupus erythematosus (SLE), who have done autopsy examination and found heart, lung and kidney damage and other multiple organs. The clinical manifestations of all cases of cardiac lesions were less than the pathological changes, including two cases of X-ray did not find abnormal heart and pulmonary circulation. The pathological basis of cardiac enlargement is that SLE affects the entire heart and pericardium; hypertension is another major factor that leads to heart enlargement. Left ventricular failure produces pulmonary hypertension; thoracic lesions and pulmonary arteriolar vitreous degeneration can lead to pulmonary hypertension.