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本文利用水平式扩散池和垂直式扩散池将含有氮酮的消炎痛生理盐水混悬液和含氮酮的消炎痛钦膏作用于大白鼠离体皮肤进行了透皮吸收实验.结果表明,生理盐水和软膏条件下,含氮酮的消炎痛在生理盐水和软膏中的透皮吸收速度为不含氮酮时的5.8和4.8倍.可见氮酮对消炎痛的透皮吸收有显著的促进作用.
In this paper, a horizontal diffusion cell and a vertical diffusion cell were used to transdermally absorb the exfoliated skin of rats with the azone-containing indomethacin saline suspension and the Azone-containing indomethacin injection. The results showed that the physiological Saline and ointment conditions, Azone-containing indomethacin in saline and ointment in the transdermal absorption rate of non-Azone-containing 5.8 and 4.8 times. Azone can be seen on the transdermal absorption of indomethacin significant role in promoting .