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用精制蝮蛇抗栓酶 (Svate - 3)治疗了 10 8例急性期脑血栓形成病人 ,治疗前后分别测定病人血清微量元素锌、铜、铬、锰、硒及体液免疫指标IgG ,IgA ,IgM及循环免疫复合物(CIC) ,同时设定对照组观察Svate - 3的临床疗效。观察结果表明 ,治疗组疗效优于对照组。测定结果表明 ,Svate - 3能使脑血栓病人血清Zn增加 (P <0 0 5) ,血清Cu减少 (P <0 0 5) ,Zn/Cu比值增加 (P <0 0 5) ,Svate - 3可使体液免疫IgA增加 (P <0 0 1)。
A total of 108 patients with acute cerebral thrombosis were treated with purified viper antithrombinase (Svate - 3). Serum trace elements such as zinc, copper, chromium, manganese and selenium were measured before and after treatment. IgG, IgA and IgM And circulating immune complex (CIC). At the same time, we set the control group to observe the clinical efficacy of Svate - 3. Observations show that the treatment group than the control group. The results showed that Svate - 3 could increase the level of serum Zn in patients with cerebral thrombosis (P <0 05), reduce serum Cu (P 0 05), increase the ratio of Zn / Cu (P 0 05), Svate - 3 IgA humoral immunity can be increased (P <0.01).