用单细胞凝胶电泳法检测了人全血在4℃储存时单个核细胞DNA损伤的情况.结果发现,细胞随储存时间延长基础损伤逐渐增高,储存0,24,48,72h时细胞损伤率分别为8 84%,18 5%,45 2%和54 3%,而细胞对H2O2的敏感性却逐渐降低.以50μmol/LH2O2处理后,其细胞损伤率在0,24,48h分别为63%,61 8%和51 5%. Single cell gel electrophoresis was used to detect the DNA damage of mononuclear cells stored in human whole blood at 4 ℃ .It was found that the basic damage of cells gradually increased with the storage time prolonged, and the cell injury rate at 0, 24, 48 and 72h Respectively, which were 8 84%, 18 5%, 45 2% and 54 3%, respectively, while the sensitivity of cells to H2O2 decreased gradually.With 50 μmol / LH 2 O 2 treatment, the cell damage rates were 63% , 61 8% and 51 5%.