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目的了解克拉玛依市免疫规划疫苗针对传染病的抗体水平,为进一步做好免疫规划工作提供科学依据。方法采用分层整群随机抽样调查法,抽取克拉玛依市3-14岁249名儿童,开展麻疹、腮腺炎、白喉、乙型肝炎(简称乙肝)和甲型肝炎(简称甲肝,)Ig G抗体水平检测。结果抗体阳性率依次为麻疹97.99%、甲肝96.38%、白喉91.16%、腮腺炎86.35%和乙肝76.71%,麻疹、腮腺炎、白喉GMC(几何抗体平均浓度)分别为1 303.59 m IU/m L、707.91 U/m L、1.03 IU/m L。不同地区白喉抗体阳性率有统计学意义(=29.686,P<0.001);不同免疫剂次儿童白喉、甲肝抗体阳性率有统计学意义(白喉=14.969,甲肝=9.906,P<0.05)。不同年龄组、不同性别儿童麻疹、腮腺炎、白喉、乙肝、甲肝抗体阳性率均无统计学意义(P>0.05);结论克拉玛依市3-14岁儿童麻疹、白喉、甲肝、腮腺炎具有较高的免疫水平,已达到卫生部规定的目标(85%),但乙肝抗体略低,建议对抗体水平低的儿童及时采取加强免疫,以提高人群的免疫屏障。
Objective To understand the antibody level of Karamay immunization vaccine against infectious diseases and provide a scientific basis for further immunization planning. Methods A total of 249 children aged 3-14 years in Karamay were enrolled in the study. The levels of IgG antibodies against measles, mumps, diphtheria, hepatitis B (Hepatitis A) and Hepatitis A (Hepatitis A, hepatitis A) Detection. Results The positive rates of antibodies were 97.99% for measles, 96.38% for hepatitis A, 91.16% for diphtheria, 86.35% for mumps and 76.71% for hepatitis B, respectively. The mean geometric geometric mean antibody concentrations of measles, mumps and diphtheria were 1 303.59 m IU / 707.91 U / m L, 1.03 IU / m L. The positive rates of diphtheria antibody in different areas were statistically significant (= 29.686, P <0.001). The positive rates of diphtheria and hepatitis A antibody in children with different immunization doses were statistically significant (diphtheria = 14.969, hepatitis A = 9.906, P <0.05). The positive rates of measles, mumps, diphtheria, hepatitis B, and hepatitis A were not significantly different in different age groups and different sexes (P> 0.05). Conclusion The measles, diphtheria, hepatitis A and mumps in children aged 3-14 years in Karamay were higher The level of immunity has reached the target set by the Ministry of Health (85%), but the hepatitis B antibody is slightly lower, and it is recommended that children with low antibody levels should be promptly boosted to raise the immune barrier of the population.