论文部分内容阅读
目的：探讨经皮微波凝固(PMCT)联合肝动脉化疗栓塞(TACE)治疗肝内胆管细胞癌(IHCC)的疗效和机制。方法：对27例未经任何治疗、由肝活检病理证实的IHCC在实时超声引导下行PMCT,再联合TACE,根据治疗后肿瘤的坏死和复发情况,决定是否重复PMCT或TACE。结果：治疗后CA199转阴率44．4%,肿瘤平均缩小率51．4%,肿瘤完全坏死率56．7%,中位生存期18个月,1年生存率66．7%,2年生存率22．9%。结论：PMCT联合TACE治疗IHCC是一种安全、有效的方法。
Objective: To investigate the efficacy and mechanism of percutaneous microwave coagulation (PMCT) combined with transcatheter arterial chemoembolization (TACE) in the treatment of intrahepatic cholangiocellular carcinoma (IHCC). Methods: Twenty-seven patients with IHCC confirmed by pathology of liver biopsy underwent real-time ultrasound-guided PMCT without any treatment. Combined with TACE, we decided whether to repeat PMCT or TACE according to the tumor necrosis and recurrence after treatment. Results: After treatment, the negative rate of CA199 was 44.4%, the average tumor reduction rate was 51.4%, the complete tumor necrosis rate was 56.7%, the median survival time was 18 months, the 1-year survival rate was 66.7%, and 2 years Survival rate of 22.9%. Conclusion: PMCT combined with TACE in the treatment of IHCC is a safe and effective method.