乙胺碘呋酮(Amiodarone, Amiodronum Atlansil, Cordarone),即安律酮。1961年由Labaz实验室研制成功,1967年临床用于治疗心绞痛。不久发现其具有抗心律失常作用,嗣后,在这方面的应用大力增加,本文拟就乙胺碘呋酮的药理及临床应用作一简要介绍。 一、药理作用 乙胺碘呋酮是苯骈呋喃的衍生物,化学名称为:2—丁基—3 〔3.5—二碘—4—(2—二乙胺乙氧基)苯甲酰基〕苯骈呋喃盐酸盐。乙胺碘呋酮的结构与甲状腺素有某些相似之处。 Amiodarone (Amiodronum Atlansil, Cordarone), antonone. 1961 Labaz laboratory successfully developed in 1967 for the treatment of angina. Soon found to have anti-arrhythmic effect, and later, in this area greatly increased the application of this paper intends amiodarone pharmacological and clinical application of a brief introduction. First, the pharmacological effects Amiodarone is benzofuran derivatives, chemical name: 2-butyl-3 [3.5-diiodo-4- (2-diethylaminoethoxy) benzoyl] benzene Furan hydrochloride. The structure of amiodarone has some similarities to thyroxine.