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目的探讨急性心肌梗死并发恶性室性心律失常(MVA)的相关危险因素。方法回顾性分析156例急性心肌梗死患者。其中并发MAV患者53例为MAV组,未并发MAV患者103例为非MAV组。对患者年龄、吸烟史、高血压、糖尿病、心肌梗死病史、心肌损伤标志物(CK、CK-MB、cTn)、血常规(WBC、RBC、PLT)、血脂(TG、TC、LDL-C、HDLC)、电解质(K+、Na+、Ca2+)、肾功能(BUN、Scr)、空腹血糖(GLU)、C-反应蛋白(CRP)、左室舒张末径(LVEDD)、室间隔厚度(LVS)、左室后壁厚度(LVP)、左心室射血分数(LVEF)等相关指标进行分析。结果 MVA组与非MVA患者年龄、CK、CK-MB、cTnI、WBC、TC、LDL-C、HDL-C、K+、Na+、Ca2+、Scr、GLU、CRP、LVEF比较差异均有统计学意义(P<0.05或P<0.01)。经Logistic回归分析,CK-MB、cTnI、K+、CRP、LVEF与急性心肌梗死并发MAV关系密切。结论高CK-MB和TnI水平、高CRP水平、低血钾、低LVEF,是急性心肌梗死并发MVA的相关危险因素,临床上应对具备相关危险因素的患者给予足够的重视。
Objective To explore the related risk factors of acute ventricular arrhythmias (MVA) in patients with acute myocardial infarction. Methods A retrospective analysis of 156 patients with acute myocardial infarction. Among them, 53 patients with MAV complicated with MAV and 103 patients with uncomplicated MAV were non-MAV. (CK, CK-MB, cTn), blood (WBC, RBC, PLT), serum lipids (TG, TC, LDL-C, (HDLC), electrolyte (K +, Na +, Ca2 +), renal function (BUN, Scr), fasting blood glucose (GLU), C-reactive protein (CRP), left ventricular end diastolic diameter (LVEDD), interventricular septum thickness Left ventricular posterior wall thickness (LVP), left ventricular ejection fraction (LVEF) and other related indicators were analyzed. Results There were significant differences in age, CK, CK-MB, cTnI, WBC, TC, LDL-C, HDL-C, K +, Na +, Ca2 +, Scr, GLU, CRP and LVEF between MVA group and non-MVA group P <0.05 or P <0.01). Logistic regression analysis showed that CK-MB, cTnI, K +, CRP and LVEF were closely related to acute myocardial infarction complicated by MAV. Conclusion High CK-MB and TnI levels, high CRP levels, hypokalemia, and low LVEF are risk factors for acute myocardial infarction complicated with MVA. Clinicians should pay enough attention to patients with relevant risk factors.