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目的应用速度向量成像技术定量评价川崎病冠状动脉瘤患儿左心室纵向及径向收缩功能。方法 37例川崎病冠状动脉瘤患儿根据冠状动脉瘤大小分为病变Ⅰ组、Ⅱ组,分别与20例正常儿童对照,采用速度向量成像技术分别测量左心室最大纵向及径向运动速度、应变及应变率;Simpson法心内膜自动跟踪测量左心室射血分数、每搏量。结果病变Ⅰ组各节段左心室最大纵向运动速度及应变率明显低于对照组(P<0.05),径向应变率明显低于对照组(P<0.05);病变Ⅱ组各节段最大纵向运动速度、应变及应变率均明显低于Ⅰ组(P<0.05),径向应变率明显低于Ⅰ组(P<0.05);各组间左心室射血分数、每搏量差异均无统计学意义。结论川崎病冠状动脉瘤患儿左心室最大纵向运动速度及纵向、径向应变率明显减低,提示心肌收缩功能受损,速度向量成像技术可以定量评价左室局部收缩功能。
Objective To quantitatively evaluate longitudinal and radial systolic function of left ventricle in children with Kawasaki disease with coronary artery aneurysm using velocity vector imaging. Methods Thirty-seven Kawasaki disease patients with coronary artery aneurysm were divided into two groups according to the size of coronary aneurysm. Group Ⅰ and group Ⅱ were compared with 20 normal children respectively. Velocity vector imaging was used to measure the maximal longitudinal and radial velocity of left ventricle, And strain rate; Simpson endocardial auto-tracking measurement of left ventricular ejection fraction, stroke volume. Results The maximum longitudinal velocity and strain rate of left ventricular in each group were significantly lower than those in control group (P <0.05), and the radial strain rate was significantly lower than that in control group (P <0.05). The maximum longitudinal (P <0.05). The radial strain rate was significantly lower than that of group Ⅰ (P <0.05). There was no statistical difference in left ventricular ejection fraction and stroke volume between groups Significance of learning. Conclusions The maximum longitudinal velocity and longitudinal and radial strain rate of left ventricular in Kawasaki disease patients with coronary artery aneurysm were significantly decreased, suggesting that myocardial contractile function was impaired. Velocity vector imaging could quantitatively evaluate left ventricular regional systolic function.