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骨髓间充质干细胞(BMSC)是目前常用于细胞移植治疗的组织工程种子细胞,很多研究致力于BMSC移植修复各种缺血梗死的机体组织。BMSC可能通过多种途径改善组织供血状况,目前认为其旁分泌促血管生成因子及具有向血管内皮细胞分化的潜能是其促血管再生的重要机制。近年来有学者提出BMSCs的旁分泌机制是促血管生成的主要机制:有研究用乳酸乙醇酸支架组合成骨样细胞与
Bone marrow mesenchymal stem cells (BMSCs) are the most commonly used tissue-engineered seed cells for cell transplantation. Many studies have been devoted to BMSC transplantation to repair various ischemic infarct tissues. BMSC may improve tissue blood supply in many ways. At present, it is thought that its potential of paracrine pro-angiogenic factors and differentiation into vascular endothelial cells is an important mechanism of angiogenesis. In recent years, some scholars have proposed paracrine mechanism of BMSCs is the main mechanism of angiogenesis: a study with lactic acid glycolic acid scaffold combination of osteoblasts and