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目的：了解我院2015年门诊口服降压药物的临床应用情况，为临床合理用药及药品管理提供依据。方法采用限定日剂量、用药频度及药物利用指数方法，对我院2015年门诊降压药物运用情况进行统计分析。结果从随机抽查的处方中发现，50岁以上患者发病率较高，<占90%；使用降压药物品种22个，处方频率前3位的抗高血压药分别为钙拮抗剂(CCB)、血管紧张素转化酶抑制剂和血管紧张素Ⅱ受体拮抗剂(ARB)；降压药物使用频率前3位分别是氨氯地平片、缬沙坦胶囊和厄贝沙坦片；用药频度前3位的分别是氨氯地平片、缬沙坦胶囊和厄贝沙坦片；治疗以CCB+ARB联合为主。结论我院降压药物应用基本合理，符合高血压用药指南；联合治疗策略值得广泛应用。“,”Objective Through investigation of oral antihypertensive drugs utilization in hospital, to provide further evidence for promoting rational medication in clinical and drug administration. Methods The use of oral antihypertensive drugs were analyzed by defined daily dose (DDD),defined daily doses (DDDs) and drug utilization index (DUI) in 2015 for outpatients in our hospital. Results In the random survey, the prevalence rate of adults aged 50 years and above was the highest by 90%. Among 22 kinds of antihypertensive drugs, the highest use frequency is calcium channel blocker(CCB), followed by angiotensin 1-converting enzyme inhibition medicine(ACEI) and angiotensin receptor blockers(ARB). Single ranking in the top three varieties of use frequency is Amlodipine Tablets, Valsartan Capsules and Irbesartan tablets, and single ranking in the top three varieties of DDDs is Amlodipine Tablets, Valsartan Capsules and Irbesartan tablets as well. The most common prescription is calcium channel blocker (CCB) combined with angiotensin receptor blockers (ARB). Conclusion The application fo antihypertensive drugs in our hospital was basically rational, in accord with guidelines for the management of hypertension, and the combined treatment strategy is recommendable.