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目的:探讨外周血癌胚胎抗原(CEA)、糖类抗原CA153、CA125在乳腺癌临床筛查及诊断中的应用价值。方法:应用ELISA法测定54例乳腺癌、50例乳腺良性肿瘤及50例健康体检者外周血CEA、CA153、CA125水平,采用受试者特异曲线(ROC)分析三种肿瘤标志物对乳腺癌筛查及诊断价值。结果:乳腺癌患者外周血CEA、CA153、CA125水平显著高于乳腺良性肿瘤及健康体检者(P<0.05)。结论:外周血CEA、CA153、CA125水平对鉴别乳腺癌具有一定的临床价值,且联合检测可提高诊断效能。
Objective: To investigate the clinical value of CEA, CA153 and CA125 in clinical screening and diagnosis of breast cancer. Methods: The levels of CEA, CA153 and CA125 in 54 cases of breast cancer, 50 cases of benign breast tumors and 50 cases of healthy volunteers were detected by ELISA. The tumor markers of breast cancer were analyzed by ROC. Check and diagnostic value. Results: The levels of CEA, CA153 and CA125 in peripheral blood of breast cancer patients were significantly higher than those of benign breast tumors and healthy controls (P <0.05). Conclusion: The levels of CEA, CA153 and CA125 in peripheral blood have some clinical value in differentiating breast cancer, and combined detection can improve the diagnostic efficacy.