硝酸盐制剂是治疗缺血性心脏病的第一线药物。舌下含用硝酸甘油治疗心绞痛,已沿用一个多世纪。而近年来,硝酸甘油经静脉给药为一更新的治疗途径,目前已在国际上广泛用于控制冠心病患者。本文着重介绍了硝酸甘油静脉给药的临床药理学,临床实践的应用指征及其效益。 Nitrate preparations are first-line drugs for the treatment of ischemic heart disease. Sublingual nitroglycerin for angina pectoris has been used for more than a century. In recent years, the intravenous administration of nitroglycerin is a newer therapeutic approach, which is widely used in the world to control patients with coronary heart disease. This article highlights the clinical pharmacology of intravenous nitroglycerin, clinical indications and benefits.