目的:应用近红外漫反射光谱法对红霉素薄膜衣片进行一致性检验。方法:使用矢量归一化对某厂家红霉素薄膜衣片进行预处理,建立一致性检验方法。结果:确定Conformity Index(CI)为3,使用一致性检验方法可以显著区分与某厂家样本主成分相同的其他厂家样本。结论:本方法快速简便,结果准确,适用于药品质量在线监控和假劣药品的快速筛查。 Objective: To verify the consistency of erythromycin film-coated tablets by near-infrared diffuse reflectance spectroscopy. Methods: Vector normalization of a manufacturer of erythromycin film-coated pretreatment, the establishment of consistency test methods. Results: A Conformity Index (CI) of 3 was determined. Consistency tests were used to significantly distinguish other manufacturers’ samples with the same principal components as a manufacturer’s sample. Conclusion: The method is rapid, simple and accurate. It is suitable for on-line monitoring of drug quality and rapid screening of counterfeit drugs.