目的：通过观察“梦戴维”高透氧夜戴型硬性角膜塑形镜的临床应用情况，评价“梦戴维”角膜塑形镜矫治青少年轻中度近视临床使用的安全性、有效性，同时分析其相关因素。方法：选择我院眼科门诊的12～18周岁轻中度近视眼青少年73例143眼，按照我院角膜塑形镜验配流程规范验配，均配戴夜戴镜片，随访1年，观察其疗效、并发症及配戴者主观症状。结果：配戴1年后配戴者主观症状基本良好；1年后裸眼视力、屈光度、角膜地形图（K值）与配戴前比较差异统计上均有显著性（P0.05）。结论：“梦戴维”角膜塑形镜矫治青少年轻中度近视是安全有效的，但必须进行规范的验配并且长期配戴必须严密观察及随诊，以确保长期治疗的安全性和有效性。“,”Aim To observe the clinical effects of rigid gas permeable contact lens for overnight orthokeratology, evaluate the safety and effectivity of orthkeratology in pre-adolescent myopes, and analyze relevant factors.MethodsSeventy-three pre-adolescent myopes(143 eyes ,aging from 12 to 18 years old) were follwed up for one year. All patient wore night orthokertology lens afer standard optometry for spectacles. The therapeutic effect and complications, subjective feeling were observed.Results All patients after one year wearing felt favorable. Uncorrected visual acuity was improved after one year, Diopters and K value were lower than past. The difference was significant(P0.05).Conclusion Orthokeratology lens are safe and effective for treating mild and middle myopia of teenager’s. But must be standard optometry for spectacles and the further study is needed to ensure the safety and effectivity for long wearing.