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目的监测支气管肺发育不良(bronchopulmonary dysplasia,BPD)生后3年内潮气呼吸肺功能动态变化,以探讨BPD对患儿远期肺功能的影响。方法收集BPD患儿生后3年内临床资料及肺功能结果,与同龄非BPD患儿对比。结果 BPD患儿生后3年内均存在肺功能异常,肺功能参数如潮气量(VT)、吸气时间(TI)、达峰时间比(TPTEF/TE)、达峰容积比(VPTEF/VE)降低,呼吸频率(RR)、呼气时间(TE)升高,与非BPD患儿比较,差异有统计学意义(P<0.05);身高及体重均较同龄非BPD儿童下降(P<0.05)。结论 BPD导致婴儿肺功能异常,并影响生长发育。
Objective To monitor the dynamic changes of pulmonary function during 3 years after birth in patients with bronchopulmonary dysplasia (BPD) to explore the effect of BPD on long-term pulmonary function in children. Methods The clinical data and pulmonary function of children with BPD within 3 years after birth were collected and compared with non-BPD children of the same age. Results Pulmonary dysfunction was found within 3 years after birth in children with BPD. The pulmonary function parameters such as tidal volume (VT), inspiratory time (TI), peak time ratio (TPTEF / TE), peak volume ratio (VPTEF / VE) (P <0.05). The height and body weight of children with non-BPD were significantly lower than those of non-BPD children (P <0.05), and the difference was statistically significant . Conclusion BPD leads to abnormal lung function in infants and affects growth and development.