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积极采取双联抗血小板聚集、抗栓治疗以及再灌注治疗,许多患者在发生ST段抬高型心肌梗死后,仍会发生不良心血管事件,其中部分心血管事件的发生与无复流有关。无复流主要有三个发病机制,即微血管的结构改变、功能改变和血管外压迫。很多危险因素,如缺血区域、缺血时间、高血压、吸烟、血脂异常、糖尿病、炎症等,均与无复流的发生相关。现详细阐述无复流的发病机制、诊断评估方法、危险因素、预防和治疗策略。“,”Despite active measures , such as double antiplatelet therapy , antithrombotics therapy and reperfusion therapy , adverse cardiovascular events will still occur after ST-segment elevation acute myocardial infarction .Part occurrence of the cardiovascular events is connected with the no-reflow phenomenon .No-reflow has three main pathogenic mechanisms , namely structural or functional change of micro-vascular and extravascular compression .This review will elaborate into these aspects in great detail .