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激活的血小板可分泌大量活性产物,对靶细胞行为有着广泛的影响。本文在复习近年来有关文献的基础上,就血小板及其活性产物在肾小球疾病中作用证据、如何改变肾小球基底膜通透选择性并促进免疫复合物沉积以及促进肾小球重建的机制作一综述。
Activated platelets can secrete a large number of active products, have a wide range of effects on the target cell behavior. On the basis of reviewing the literature in recent years, this paper presents evidence on the role of platelets and their active products in glomerular diseases, how to change the permeability selectivity of glomerular basement membrane and promote the deposition of immune complexes and promote the glomerular reconstruction Mechanism for a review.