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补碘预防碘缺乏性疾病的益处已不言而喻,但也发生甲状腺毒症和引起甲状腺功能减退症(甲减)的甲状腺炎等不良反应。碘致甲状腺炎以前的证据仅来自实验性研究、病理学检查和横断面流行病学调查。本期发表的滕卫平等在中国轻度碘缺乏、超足量碘补充和碘过量摄取地区的3个人群的研究已证实随着较高的碘摄取,甲状腺自身免疫和亚临床甲减的发病率呈轻度、但已有统计学意义的上升。然而,临床甲减的发病率并未见升高。这些发现再次从临床和公共卫生方面消除了人们的疑虑,证实了补碘方案对人类健康会产生巨大的效益而风险甚小。
The benefits of iodine supplementation to prevent iodine deficiency disorders are self-evident, but there are also side effects such as thyrotoxicosis and thyroiditis that cause hypothyroidism (hypothyroidism). Previous evidence of iodine-induced thyroiditis only came from experimental studies, pathological examinations and cross-sectional epidemiological investigations. In this issue of Teng Weiping et al in China, mild iodine deficiency, excess iodine supplement and iodine overdose areas of the three population studies have confirmed that with higher iodine intake, thyroid autoimmune and subclinical hypothyroidism incidence Rate was mild, but a statistically significant increase. However, the incidence of clinical hypothyroidism has not seen an increase. Again, these findings have aroused people’s concerns from both clinical and public health perspectives, confirming the low risk of the iodine-rich regimen having enormous benefits to human health.