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目的研究临床医护人员鼻前庭带菌情况及其耐药性,为制定有效控制措施提供依据。方法采用现场采样和细菌分离鉴定方法,对天津市部分不同级别医疗机构重点科室医务人员进行了调查。结果现场采集鼻前庭标本945份,共分离到革兰阴性菌332株,分离率为35.13%。鼻前庭检出的革兰阴性菌对临床常用抗菌药物耐药率比较高,总平均耐药率为39.46%;其中多重耐药菌株占25.30%,敏感菌株占46.99%。结论天津市医疗机构临床医务人员鼻前庭革兰阴性菌携带率较高,且普遍耐药,应当加强医务人员自身带菌情况监测和控制措施。
Objective To study the incidence of nasal vestibular bacteria and drug resistance in clinicians and provide the basis for effective control measures. Methods Field sampling and bacterial isolation and identification methods were used to investigate the medical staffs in key departments of different levels of medical institutions in Tianjin. Results 945 specimens of nasal vestibule were collected on site, and 332 strains of Gram-negative bacteria were isolated. The isolation rate was 35.13%. Gram-negative bacteria detected in the nasal vestibule were relatively resistant to commonly used antibiotics, with a total average resistance rate of 39.46%. Among them, multi-drug resistant strains accounted for 25.30% and susceptible strains accounted for 46.99%. CONCLUSIONS: The medical rate of nasopharyngeal gram-negative bacteria in medical institutions in Tianjin is relatively high and generally resistant. It is necessary to strengthen the monitoring and control measures of medical personnel carrying their own bacteria.