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利用抗人 T 细胞单克隆抗体,通过免疫组织化学酶标记技术,对口腔癌宿主体内 T 淋巴细胞及其亚群的分型、定位和计数分析是近年来关于口腔恶性肿瘤细胞免疫学研究的重大进展。多数报道显示口腔癌宿主外周血中 T 淋巴细胞计数及百分比有增高趋势,在癌灶组织中 T 淋巴细胞占浸润细胞的大多数,且分布于癌巢周围,并与癌临床的分期与组织学分化有关。此外,两类主要 T 亚群细胞计数比较,T 抑制细胞一般多于 T 辅助细胞。
The use of anti-human T-cell monoclonal antibodies and immunohistochemical enzymatic labeling techniques to classify, locate and count T-lymphocytes and their subpopulations in oral cancer hosts is a major area of research in oral cancer immunology. progress. Most reports have shown that T lymphocyte counts and percentages in the peripheral blood of oral cancer host are increasing. In the tumor tissue, T lymphocytes account for the majority of infiltrating cells, and they are distributed around the cancer nest, and are associated with the staging and histological division of the cancer. Related to. In addition, compared with the cell counts of the two major T subpopulations, T suppressor cells are generally more than T helper cells.