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自由基是具有不配对价电子的分子、原子或离子,它们的特点是寿命短,化学性质非常活泼。近20年来关于自由基与生物学和医学的关系已经有了不少了解,并且正受到生物学家和医学家的重视。一系列的研究表明,自由基广泛存在于生物机体中,它参与某些正常生理活动过程,但也对机体起损伤作用,许多疾病可能与自由基对机体的直接或间接的损伤相联系。这方面的研究涉及到多种学科,如生物化学、生物物理学、药理学、毒理学、细胞生物学、分子生物学、放射生物学等,它与血液学的关系也十分密切,已有证据表明,某些贫血疾病和白血病等与自由基有重要的联系,现分别介绍如下。
Free radicals are molecules, atoms or ions that have unpaired electron pairs and are characterized by their short lifetime and very chemical properties. In the past 20 years, there has been a lot of understanding about the relationship between free radicals and biology and medicine, and it is being paid great attention by biologists and medical scientists. A series of studies have shown that free radicals are widely distributed in the biological body, it is involved in some normal physiological processes, but also on the body damage, many diseases may be associated with free radicals on the body’s direct or indirect damage. Research in this area involves a variety of disciplines, such as biochemistry, biophysics, pharmacology, toxicology, cell biology, molecular biology, radiobiology, and its relationship with hematology is also very close, there is evidence Shows that some anemia and leukemia and other free radicals have an important connection, are introduced as follows.