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5. Syntheses of Nucleoside Derivatives Containing Fmoc- or Trityl-protected Amino Acids

Syntheses of Nucleoside Derivatives Containing Fmoc- or Trityl-protected Amino Acids

来源 :高等学校化学研究（英文版） | 被引量 : 0次 | 上传用户：guaiguaikeleo

【摘 要】

：

Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids via N,N-dicyclohexyl-carbodiimide(

【作 者】

：

GUO Hui ZOU Wu-xin JI Qi MA Yu 

【机 构】

：

Department of Chemistry

【出 处】

：

高等学校化学研究（英文版）

【发表日期】

：

2004年期

【关键词】

：

Nucleoside Amino acid Esterification 2′ 3′-O-Isopropylidene-nucleoside 

【基金项目】

：

国家自然科学基金

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论文部分内容阅读

Facile direct esterification reactions between 2′,3′-O-isopropylidene-nucleosides and Fmoc- or trityl-protected amino acids via N,N-dicyclohexyl-carbodiimide(DCC) mediated condensation are described. These reactions offer a mild and convenient method to synthesize aminoacylated nucleoside derivatives.

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