The kinetics of the decomposition of dimethylhexane-1,6-dicarbamate to 1,6-hexamethylene diisocyanate was studied. A consecutive reaction model was established and the reaction orders for the two steps were confirmed to be 1 and 1.3 by the integral test method and the numerical differential method, respectively. The activation energies of the two steps were(56.94 ± 5.90) k J·mol-1and(72.07 ± 3.47) k J·mol-1with the frequency factors exp(12.53 ± 1.42) min-1and(14.254 ± 0.84) mol-0.33·L0.33·min-1, respectively. Based on the kinetic model obtained, the progress of the reaction can be calculated under given conditions. The kinetics of the decomposition of dimethylhexane-1,6-dicarbamate to 1,6-hexamethylene diisocyanate was studied. A consecutive reaction model was established and the reaction orders for the two steps were confirmed to be 1 and 1.3 by the integral test method and The numerical differential method, respectively. The activation energies of the two steps were (56.94 ± 5.90) ​​kJ · mol- 1and (72.07 ± 3.47) kJ · mol- 1with the frequency factors exp (12.53 ± 1.42) min- 1and 14.254 ± 0.84) mol-0.33 · L0.33 · min-1, respectively. Based on the kinetic model obtained, the progress of the reaction can be calculated under given conditions.