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目的:探讨宫颈电环切除术对CIN患者术后妊娠结局的影响。方法:收集2000年至2007年因宫颈高度病变行LEEP术、术后成功受孕并已终止妊娠的妇女102例作为病例组。其中,按电切深度分为10～20mm组(76例)和21～25mm组(26例);按电切宽度分为15～20mm组(30例)和21～40mm组(72例)。随机抽取同期门诊无宫颈治疗史的健康孕产妇104例为对照组。追踪并比较各组自然流产率、早产率、胎膜早破率、低出生体重率以及剖宫产率。结果:病例组及对照组分娩孕周均>28周;两组自然流产率、早产率、胎膜早破率、剖宫产率和分娩孕周均无显著差异(P均>0.05);病例组新生儿平均体重显著高于对照组[(3.45±0.29)kg vs(3.32±0.35)kg,P<0.05]。宫颈电切深度为10～20mm组的妊娠结局与21～25mm组无显著差异(P>0.05);宫颈电切宽度为15～20mm组的妊娠结局与21～40mm组亦无显著差异(P>0.05)。结论:宫颈电环切除术对术后妊娠妇女的妊娠结局无明显影响。宫颈电环切除深度<25mm、宽度<40mm时,患者术后妊娠的自然流产、早产、胎膜早破、小于胎龄儿等不良结局发生率无明显增加。
Objective: To investigate the effect of cervical electrocorticoid excision on postoperative pregnancy outcomes in patients with CIN. Methods: A total of 102 women who underwent LEEP due to cervical lesions from 2000 to 2007 were enrolled in this study. Among them, the patients were divided into 10-20 mm group (76 cases) and 21-25 mm group (26 cases) according to the depth of resection. The patients were divided into 15-20 mm group (30 cases) and 21-40 mm group (72 cases) according to the width of the resection. A total of 104 healthy pregnant women with no history of cervical cancer during the same period were randomly selected as the control group. The spontaneous abortion rate, premature birth rate, premature rupture of membranes, low birth weight rate and cesarean section rate were tracked and compared. Results: The gestational age of the cases and control groups were both> 28 weeks. There was no significant difference in spontaneous abortion rate, premature birth rate, premature rupture of membranes, cesarean section rate and gestational age between two groups (all P> 0.05) The average newborn weight of the group was significantly higher than that of the control group [(3.45 ± 0.29) kg vs (3.32 ± 0.35) kg, P <0.05]. There was no significant difference in the pregnancy outcome between the group of 21 ~ 25mm and the group of 10 ~ 20mm cervical excision (P> 0.05) 0.05). Conclusion: Cervical electrocautery excision has no significant effect on the pregnancy outcomes of postoperative pregnant women. Cervical ring excision depth <25mm, width <40mm, the patient’s postoperative pregnancy spontaneous abortion, premature birth, premature rupture of membranes, less than gestational age children and other adverse outcomes no significant increase in the incidence.