四组分汉栖反应提供了得到医药上重要的二氢吡啶化合物的机会。为了扩展这一方法的用途,我们已经开发了在有机催化剂条件下,具有好的产率和优良的ee’s的路线。通过催化剂筛选,我们发现 The four component hare reaction provides the opportunity to obtain medically important dihydropyridine compounds. In order to extend the use of this method, we have developed a route with good yield and excellent ee’s under organic catalyst conditions. We found through catalyst screening