中医用白前胡治疗营养性疾病、支气管病及胸疼,还可能缓解心绞痛,因而作者做实验观察了白前胡对平滑肌的作用。 实验结果表明,白前胡的乙醚溶解组分对豚鼠迥肠由乙酰胆碱和组织胺引起的收缩有很强的非竞争性对抗作用。其有效成份为香豆素类,其中仅Pd-Ⅰa有钙拮抗作用,Pd-Ⅱ和Pd-Ⅲ无此作用。 1.Pd-Ⅰa非竞争性地抑制乙酰胆碱引起的豚鼠迥 Chinese medicine with Bai Qianhu treatment of nutritional diseases, bronchial diseases and chest pain, but also may relieve angina pectoris, so the authors experimentally observed the effect of Baiqianhu on the smooth muscle. The experimental results show that the ethanol extract of Baiqianhu has a strong noncompetitive antagonistic effect on the contractions induced by acetylcholine and histamine in guinea pig colon. The active ingredient is coumarins, of which only Pd-Ia calcium antagonism, Pd-Ⅱ and Pd-Ⅲ without this effect. 1.Pd-Ia non-competitive inhibition of acetylcholine-induced guinea pig Jiong