八十年代起肿瘤免疫治疗(IT)有巨大的变化与进展。概念上:扩大为生物学治疗(BT)、生物学反应调节疗法(BRMT)——可能成为肿瘤的第四大疗法。主攻方向:从非特异性主动免疫治疗转向被动免疫治疗——给带瘤宿主输注抗瘤单抗(包括“导向”疗法)或具抗瘤活性的免疫细胞(AIT),后者更有希望, Since the 1980s, there have been tremendous changes and advances in cancer immunotherapy (IT). Conceptually: expanded to biological therapy (BT), biological response modulation therapy (BRMT) - may become the fourth largest cancer therapy. Main direction of attack: from non-specific active immunotherapy to passive immunotherapy - infusion of tumor-bearing host anti-tumor monoclonal antibodies (including “guided” therapy) or immune cells with anti-tumor activity (AIT), which is more promising,