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在我国神经管畸形(NTDs)高发的北方和低发的南方城乡地区,分别进行了婚检妇女的叶酸营养状况监测,结果发现妇女血清叶酸总缺乏率为23.6‰,红细胞叶酸总缺乏率为298.1‰。红细胞叶酸缺乏率高于血清叶酸缺乏率。南方妇女叶酸缺乏率低于北方妇女,城市妇女叶酸缺乏率低于农村。夏、秋、冬、春季妇女的叶酸缺乏率不同。叶酸营养状况与神经管畸形发病率存在着负相关。
In the north of China with high incidence of neural tube defects (NTDs) and low incidence of southern urban and rural areas, respectively, the women of premarital women’s folic acid nutrition monitoring results showed that women with total serum folate deficiency was 23.6 ‰, the total lack of erythrocyte folic acid was 298.1 ‰ . Erythrocyte folic acid deficiency rate is higher than the serum folic acid deficiency rate. The rate of folic acid deficiency in southern women is lower than that in northern women, and the rate of folic acid deficiency in urban women is lower than that in rural areas. Summer, autumn, winter and spring women’s folic acid deficiency rate is different. There was a negative correlation between folic acid nutritional status and the incidence of neural tube defects.