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目的探讨对伊立替康致延迟性腹泻的患者开展有效药学监护的方法。方法临床药师通过对症对因治疗及基因检测等方式,参与应用伊立替康化疗出现延迟性腹泻患者的治疗。结果在临床药师参与治疗下,患者均安全度过化疗期。结论药学监护可提高化疗药物治疗的安全性和有效性。
Objective To explore a method of effective pharmacological care in patients with irrigant-induced delayed diarrhea. Methods The clinical pharmacists participated in the treatment of patients with delayed diarrhea by irinotecan chemotherapy through symptomatic treatment and genetic testing. Results In the participation of clinical pharmacists under treatment, patients were safely over the chemotherapy period. Conclusion Pharmacokinetic monitoring can improve the safety and effectiveness of chemotherapy drugs.