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重症肌无力 (MG)是主要累及神经肌肉接头处突触后膜上乙酰胆碱受体 (ACh R)的自身免疫性疾病 (AID)。曾认为针对 ACh R的自身抗体 ,亦即体液免疫是 MG唯一的致病因素 ,随着免疫学研究的深入进展愈加认识到 :自身抗体不能解释 MG自身免疫应答启动和发展的原因。 MG免疫应答是一?
Myasthenia Gravis (MG) is an autoimmune disease (AID) that mainly affects the acetylcholine receptor (AChR) on the postsynaptic membrane at the neuromuscular junction. It has been recognized that autoantibodies directed against ACh R, humoral immunity is the sole causative agent of MG. As immunological research progresses, it is increasingly recognized that autoantibodies can not explain the cause of the initiation and progression of MG autoimmune response. MG immune response is one?