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目的研究复发性单纯疱疹性角膜炎患者外周血Ｔ－淋巴细胞亚群变化与血清可溶性白细胞介素－２受体（ＳＩＬ－２Ｒ）水平的关系。方法测定了３０例复发性单纯疱疹性角膜炎患者外周血Ｔ－淋巴细胞亚群，同时用酶联免疫吸附试验检测ＳＩＬ－２Ｒ水平。结果复发性单纯疱疹性角膜炎患者ＣＤ３、ＣＤ４／ＣＤ８均值与正常对照组相比明显降低；ＳＩＬ－２Ｒ与对照组比较显著增高。结论复发性单纯疱疹性角膜炎患者体内免疫功能低下，ＳＩＬ－２Ｒ水平升高可能是其原因之一，这也为免疫治疗提供了一定依据。
Objective To study the relationship between the changes of T-lymphocyte subsets in peripheral blood and serum levels of soluble interleukin-2 receptor (SIL-2R) in patients with recurrent herpes simplex keratitis. Methods T-lymphocyte subsets in peripheral blood were measured in 30 patients with recurrent herpes simplex keratitis and the level of SIL-2R was detected by enzyme linked immunosorbent assay (ELISA). Results The mean of CD3 and CD4 / CD8 in patients with recurrent herpes simplex keratitis was significantly lower than that in the control group. The level of SIL-2R was significantly higher in the control group than in the control group. Conclusion In patients with recurrent herpes simplex keratitis, immunosuppression and elevated SIL-2R levels may be one of the reasons for this. This may provide a basis for immunotherapy.