为探究先兆子痫(PE)发病的起因及机制,加强对该病的预防,拓宽临床治疗的理论依据。检索国外近年对PE发病机制的研究并归纳总结。认为PE是一种妊娠并发症,其发病不仅和免疫反应、母体炎性反应、易感基因的遗传有关,还和种族、肥胖、营养、生活方式、精神状态等多种因素有关。PE是多因素引起的妊娠并发症,对其发病机制目前尚无定论。 To explore the pathogenesis and mechanism of preeclampsia (PE), to strengthen the prevention of the disease and broaden the theoretical basis for clinical treatment. Retrieve the foreign study on the pathogenesis of PE in recent years and summarize. PE is considered to be a pregnancy complication, the incidence of which is not only related to the immune response, maternal inflammatory response and gene inheritance of susceptibility genes, but also to factors such as race, obesity, nutrition, lifestyle and mental status. PE is a multifactorial pregnancy complications, its pathogenesis is not yet conclusive.